16alpha-Hydroxyprednisolone CAS NO.13951-70-7

Prednisolone is a synthetic effect of glucocorticoid, and prednisone is similar to the role, has anti-inflammatory, anti allergic effect and so on, the anti-inflammatory effect of strong, water and salt metabolism is very weak. This product is hydroxyl compound (hydroxyl in 11 place), the effect of local application is better, and it also applies to patients with liver dysfunction. Oral absorption of fast and complete, 1 hours of blood concentration peak, the plasma protein binding rate of 95% to 90%, half-life of about 200 minutes. Can enter the fetal circulation, appear in the milk of the dosage of 0.07% ~ 0.23%. After the intrahepatic metabolism, the main excreted from the kidney, which accounted for more than 20% of the drug. Suitable for the treatment of eczema, dermatitis and other allergic diseases, lupus erythematosus, dermatomyositis and other connective tissue diseases.

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